Bury FC's main sponsor Bury Council will not renew its deal with the club at the end of the current football season.
The council has been the club's main sponsor since an original three-year deal was signed in 2009 and extended in 2012.
The deal runs out at the end of the current season and the two parties said they have "amicably decided to go their separate ways".
Bury Council leader Mike Connolly said: "It's been an honour to work with Bury FC, who have a tremendous record of working in the community to encourage people into sport and to take up healthier lifestyles. Many tens of thousands of local people have benefitted from this partnership agreement, and it’s been a good deal for both sides."
But he added it was "no secret that the council is having to make huge budget savings".
Glenn Thomas, chief executive officer of Bury FC, said: "As a club, we do not see this as the end of a book, but the start of a new chapter."
"The council stepped in during a horrific financial period for the club and helped keep the community together over a significant period of its history. For that, the club will always be grateful."
"Unfortunately, due to financial cutbacks, the council made it clear that they could no longer support the club financially, but made it clear that it would support the club in as many other ways as they could as we continue to rebuild the club both on and off the pitch."