Friends and family of the victims are expected to attend the service which will take place in Centenary Square at 11:00 am.
The commemoration will be led by the Lord Mayor of Bradford, Naveeda Ikram.
An investigation held into the disaster found the fire had probably been caused by a lit cigarette dropped under the all-wooden stand, igniting litter underneath the steps.
The event led to a wholesale review of safety standards in grounds and many of the improvements around the country were a direct result of the enquiry after the fire.
Mrs Ikram said it was important for local residents to remember each anniversary of the tragedy.
"In some ways it touched the lives of most people in the district and people need to reflect and mark the occasion," she said.
Local MPs, Bradford City footballers and representatives of the emergency services are also expected to attend.